Volume 20 Number 12 December 2014 Case Presentation Nevus lipomatosus superficialis release_z7xsmv45dfhdxl5f26ukf3h3de

by Randie Kim, Mary Stevenson, Christopher Hale, Shane Meehan, Karen Chernoff, Julie Schaffer

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Nevus lipomatosus superficialis is an uncommon cutaneous hamartoma that is characterized by the presence of adipose tissue within the reticular dermis. We describe a 15-year-old boy with a three-year history of the classic type of nevus lipomatosus superficialis, which presented as linear arrays of soft, cerebriform papulonodules and plaques in the right inguinal fold. Investigation for chromosomal aberrations and dysregulation of Wnt signaling may provide insights into the pathogenesis of this hamartoma. Treatment is usually with surgical excision although successful use of other modalities has been described. Case synopsis History: A healthy 15-year-old boy presented to the Pediatric Dermatology Clinic at the Skin and Cancer Unit for evaluation and management of exophytic plaques in the right inguinal fold. These asymptomatic lesions had been slowly enlarging since they first appeared at 12 years of age.
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