Cutaneous response to dinitrochlorobenzene in patients with genito-urinary cancers release_yl3li7hkgff7fdjg3euykuriba

by H Duclos, L Schwarzenberg, S H Duclos, H Hugues, R Kuss

Published in Biomedicine / [publiee pour l'A.A.I.C.I.G.].

1977   Volume 27, Issue 1, p43-7


The aim of the present study is to analyse the response in patients with cancer of the urogenital region to a primary antigen 2-4 dinitrochlorobenzene (DNCB). A total of 69 patients with neoplastic disease were studied (13 cases with kidney cancer, 34 cases with bladder cancer, 13 cases with prostatic cancer, 5 cases with testicular cancer, one case with penis cancer, and 3 cases with cancer of the cervix, comparatively with 13 patients with non-malignant urological diseases. Whereas in the control group, 78% of the patients gave a positive skin reaction to DNCB, 15% of the patients with kidney cancer, 56% of the patients with bladder cancer, 69% of the patients with prostatic cancer and 60% of the patients with testicular cancer gave a positive reaction. If we consider the stages of the disease, the reaction was positive, in 91% of bladder cancer at stage I and in 47% at stages II and III in 100% of prostatic cancer at stage I and in 62% at stages II and III, in 60% of testicular cancer at stage IV (but 100% of seminomas and 0% of dysembryomas have a positive reaction). It would therefore seem that a correlation exists between the degree of the extension of the disease and the skin reaction to DNCB.
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Type  article-journal
Stage   published
Date   1977-01-31
Language   en ?
PubMed  856314
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ISSN-L:  0300-0893
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