We considered the problem of the combined pathology of the thyroid gland and the cardiovascular system, which is currently quite often observed. The main features of cardiovascular diseases in subclinical thyroid dysfunction are presented. The authors highlighted the theory of changes in the daily rhythms of secretion of thyroid hormones as the initial manifestations of thyroid dysfunction. Currently, there is the increase of interest in the study of biological rhythms and their changes in the pathology. Special attention was paid to the role of cellular and humoral mechanisms of regulation of biorhythms and their influence on the development and progression of cardiovascular diseases. There are presented the results of experimental evidences, pilot and prospective studies on biorhythmic changes among patients with coronary heart disease, atrial fibrillation, and chronic heart failure. The features of the rhythmic activity of the thyroid gland in cardiovascular pathology are described. In conclusion, the authors indicate that a deeper study of the individual biorhythmic characteristics would help to introduce an additional view of the mechanisms of development and progression of diseases and create prospects for introducing new effective methods of treatment.
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