What do we know about DNA mechanics so far? release_wcfzpxhtifhjjf35uvpdnsugua

by Abhishek Aggarwal, Supriyo Naskar, Anil Kumar Sahoo, Santosh Mogurampelly, Ashok Garai, Prabal K. Maiti

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The DNA molecule, apart from carrying the genetic information, plays a crucial role in a variety of biological processes and find applications in drug design, nanotechnology and nanoelectronics. The molecule undergoes significant structural transitions under the influence of forces due to physiological and non-physiological environments. Here, we summarize the insights gained from simulations and single-molecule experiments on the structural transitions and mechanics of DNA under force, as well as its elastic properties, in various environmental conditions, and discuss appealing future directions.
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Type  article
Stage   submitted
Date   2020-06-01
Version   v1
Language   en ?
arXiv  2006.00822v1
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