Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes release_utt5o7oyjvhe3aam4mt5nibjdi

by Qianfa Jia, Yunfei Lan, Xin Ye, Yinhe Lin, Qiao

Published in RSC Advances by Royal Society of Chemistry (RSC).

2020   Volume 10, Issue 49, p29171-29174


An efficient [4 + 2] benzannulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes was achieved under metal-free reaction conditions selectively delivering a wide range of polyfunctional benzenes in high yields respectively (up to 94% yield).
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Type  article-journal
Stage   published
Date   2020-08-06
Language   en ?
DOI  10.1039/d0ra05251e
PubMed  35521133
PMC  PMC9055964
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ISSN-L:  2046-2069
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