One-step light-up metabolic probes for in situ discrimination and killing of intracellular bacteria release_uktbfjlrvrd4vgsidoqqqu5lya

by Eric Y. Yu, Michelle M. S. Lee, Joe H. C. Chau, Kristy W. K. Lam, Hojeong Park, Ryan T. K. Kwok, Jacky W. Y. Lam, Yuanyuan Li, Tang, Benzhong

Published in Materials Chemistry Frontiers by Royal Society of Chemistry (RSC).

2022  

Abstract

TPEPy-Ala and TPAPy-Kdo with metabolic moieties can be directly incorporated into the bacterial cell envelopes and light up intracellular bacteria. Additionally, the metabolic probes can effectively eliminate labeled bacteria <jats:italic>in situ</jats:italic> with minimal host cell cytotoxicity <jats:italic>via</jats:italic> photodyanmic therapy.
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Type  article-journal
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Year   2022
Language   en ?
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ISSN-L:  2052-1537
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