Biological Sciences and Physics Unified: Internal Evolution and Urging the Second Scientific Revolution release_uhyodnklvjcgbp3o2lpero7mei

by Arash Sadri

Published by Zenodo.

2021  

Abstract

Abstract: Why are there several sciences instead of only one? Are all sciences reducible to the "most fundamental" one, physics? Should we try to do so now that we have the required tools? Why our ancestors could discover effective drugs that we still rely on, thousands of years ago; and we, with incomparably advanced equipment and knowledge, are desperate to do so? Why has biology, e.g., neuroscience and genomics, failed in unraveling the workings of organisms despite spending billions of hours and dollars on gathering data? Why can't we even "reproduce" our results? I show that the current ontological and methodological attitudes toward biological phenomena are flawed. I present emergent bound box theory by following the second law of thermodynamics and selection's simple core: truism-law-of-survival. It explains the evolution of organisms' internal workings and provides the first ab initio scientific framework for biological sciences, including medical, psychological, and social sciences. It is backed up by diverse evidence from Shannon and integrated information theories, computational complexity, decoherence and quantum Darwinism, effective field theories, deep learning, stability of strange attractors, and discovering that despite decades of dominance, the share of reductionist "rational" drug design from all approved drugs is less than 9%. New outlooks appear on long-debated dilemmas: machine metaphor of organisms; the "replication crisis"; Ockham's razor, simplicity, "beauty," and truth; tautology problem and a new synthesis of Darwinism; definition and origin of "life"; Laplace's demon; emergence; "levels of organization"; "downward causation"; "intelligent design"; and skepticism and the post-truth. I demonstrate applying the framework for COVID-19 by a machine learning-based cheminformatics meta-analysis using systematic review and interactome-wide consensually docked 4D-QSAR. I discuss how mistaking products of science for science has led to rote science, useless and even harmful education, intellectu [...]
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Date   2021-11-29
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