Design and fabrication of 125I seeds for brachytherapy using capillary-based microfluidic technique
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Yuan Wang, Miao Zhang, Tong Song, Zhenqi Chang
Abstract
<jats:title>Abstract</jats:title>
A new kind of <jats:sup>125</jats:sup>I seeds with a core-shell structure were synthesized by an easy assembling–disassembling coaxial capillaries microfluidic device. The dose distribution of a <jats:sup>125</jats:sup>I brachytherapy source fabricated by arranging six <jats:sup>125</jats:sup>I seeds collinearly within a cylindrical titanium capsule was simulated by modelling the source in a water phantom using Monte Carlo N-Particle Transport code. The influence of the motion and the core size of the <jats:sup>125</jats:sup>I seeds on the dose distribution was also studied in this work.
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