International journal of Applied Pharmaceutical and FORMULATION, DEVELOPMENT AND EVALUATION OF
As the vaginal walls become thinner and drier and lose some of the folds that allow them to stretch, some women never notice any symptoms. Others may experience a burning sensation, a feeling of dryne itching, or a thin, watery discharge. the good news is that effective treatment options are available. These include different forms of low estrogens applied directly to the vagina, as well as non made to formulate robust vaginal tablets suitable for scale up manufacturing and commercial use. Preliminary trials were planned using different grades of Hypromellose which property and compressibility but a variation in release profile form tablet o tablet. Seeing this later it was decided to formulate the tablet using Low viscosity polymer for better drug release and uniformity. formulation, falls within the USP specification. that the tablet dosage form was successfully formulated and it has matched the target dissolution profile with specific time point with innovators patent and the final optimized formulation has shown the expected result for all the evaluation parameters.
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