INCREASED EFFECTIVENE USEFULNESS OF DILATATION WITH INTRALESIONAL STEROID INJECTIONS IN CORROSIVE OESOPHAGEAL STRICTURES TREATMENT release_oew6vsbcrfagdo4ddkgpuogjdq

by Dr. Amir Akram, Dr. Waqas Ahmad, Dr. Muhammad Ali Rathorde

Published by Zenodo.

2019  

Abstract

<strong><em>Objectives: </em></strong><em>The research objective is the comparison of the effectiveness of intralesional steroid injection with dilatation VS with dilatation only while treating corrosive oesophageal strictures.</em> <strong><em>Method: </em></strong><em>We conducted this randomized controlled trial at Services Hospital, Lahore (October 2017 to November 2018). We took 60 patients (15 – 50) years' age having either gender and divided them into two groups; Group-A and Group-B using lottery method. We performed endoscopic dilatation in Group-A and Intra-lesional Triamcinolone injection with dilatation in Group-B. We followed-up the endoscopic dilatation for every 02 weeks. Using SPSS software, we analyzed the collected data.</em> <strong><em>Results: </em></strong><em>We took 60 patients, dividing into two groups, each consisting of an equal number (30 or 50%) of patients. We recorded the overall mean age as (32.6 ± 10.6) years among all patients with (1.7:1) of male to female ratio. The mean stricture length at baseline of Group-A (dilatation) and Group-B (combination) was (23.3 ± 2.2 cm) and (24.2 ± 3 cm) respectively. The mean length of stricture in Group-A and Group-B was (11.2 ± 3 cm) and (5.33 ± 3 cm) respectively with (P-value = 0.0001).</em> <strong><em>Conclusion: </em></strong><em>The combination group (Oesophageal + dilatation) was more effective comparing to dilatation only group.</em> <strong>Keywords: </strong><em>Intra-lesional Steroid Injection (ILSI), Corrosive Oesophageal Strictures (COS), Stricture Length (SL), and Oesophageal Strictures (OS).</em>
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