Vascular Inflammation and Endothelial Dysfunction in Experimental Hypertension release_o6nhp6pdxrf6tauiys3dhl5chi

by Carmine Savoia, Lidia Sada, Luigi Zezza, Lorenzo Pucci, Francesco Maria Lauri, Alberto Befani, Alessandro Alonzo, Massimo Volpe

Published in International Journal of Hypertension by Hindawi Limited.

2011   Volume 2011, p1-8

Abstract

Essential hypertension is characterized by increased peripheral vascular resistance to blood flow. The endothelium is a crucial regulator of vascular tone. Its function is impaired in patients with hypertension, with reduced vasodilation, increased vascular tone associated with a proinflammatory and prothrombotic state. Low-grade inflammation localized in vascular tissue is therefore recognized as an important contributor to the pathophysiology of hypertension, to the initiation and progression of atherosclerosis as well as to the development of cardiovascular diseases.
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Type  article-journal
Stage   published
Year   2011
Language   en ?
DOI  10.4061/2011/281240
PubMed  21915370
PMC  PMC3170891
Wikidata  Q35207893
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