We are pleased to see the active discussion around our study on the relationship between mandatory stay- at- home and business closures and COVID-19 spread.1 In this response, we address issues raised in three letters.2-4 The claim that the study had sample size of n=10 countries is incorrect.2 Each of the 16 regression models represented in Figure 4 included, on average, 1,362 data points (range 771-3,493) on 52 subnational units (range 27-129). Each panel regression is, in effect, a "mini-meta-analysis": the effect size is evaluated within each subnational unit, and the overall effect size is estimated from a pooling of these "within" effects. So while we aggregated the results to 10 countries, the sample size is not n=10.
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