Severe digestive pathology associated with chronic Chaga's disease in Ecuador: report of two cases release_l2rpz7u5vrejthq3zmsc5naxnm

by Angel G. Guevara, José W. Eras, Marcelo Recalde, Luis Vinueza, Philip J. Cooper, Ali Ouaissi, Ronald H. Guderian

Published in Revista da Sociedade Brasileira de Medicina Tropical by FapUNIFESP (SciELO).

1997   Volume 30, p389-392

Abstract

DNA extracted from peripheral blood of two Ecuadorian patients showing severe digestive pathology was amplified by the polymerase chain reaction using a Trypanosoma cruzi specific oligonucleotide primers derived from the primary sequence of a cDNA encoding for a 24 kDa excretory/secretory protein. The positive PCR results together with the clinical findings confirmed that both patients had a digestive pathology due to Chagas' disease. This pathology could be more frequent than previously described in the chagasic endemic regions of Andean countries.
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