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A novel pathway linking plasma membrane and chloroplasts is co-opted by pathogens to suppress salicylic acid-dependent defences release_fs3cghvw2rf7za2djciywamctm

by Laura Medina-Puche, Huang Tan, Vivek Dogra, Mengshi Wu, Tabata Rosas-Diaz, Liping Wang, Xue Ding, Dan Zhang, Xing Fu, Chanhong Kim, Rosa Lozano-Duran

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abstracts[] {'sha1': '1ec73e8773278869a1cc8a3267f084905da690ff', 'content': 'Chloroplasts are crucial players in the activation of defensive hormonal responses during plant-pathogen interactions. Here, we show that a plant virus-encoded protein re-localizes from the plasma membrane to chloroplasts upon triggering plant defence, interfering with the chloroplast-dependent activation of anti-viral salicylic acid (SA) biosynthesis. Strikingly, we have found that plant pathogens from different kingdoms seem to have convergently evolved to target chloroplasts and impair SA-dependent defences following an association with membranes, which is based on the co-existence of two subcellular targeting signals, an N-myristoylation site and a chloroplast transit peptide. This pattern is also present in plant proteins, at least one of which conversely activates SA defences from the chloroplast. Taken together, our results suggest that a pathway linking plasma membrane to chloroplasts and activating defence exists in plants, and that such pathway has been co-opted by plant pathogens during host-pathogen co-evolution to promote virulence through suppression of SA responses.', 'mimetype': 'application/xml+jats', 'lang': None}
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{'index': 1, 'creator_id': None, 'creator': None, 'raw_name': 'Huang Tan', 'given_name': 'Huang', 'surname': 'Tan', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 2, 'creator_id': None, 'creator': None, 'raw_name': 'Vivek Dogra', 'given_name': 'Vivek', 'surname': 'Dogra', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 3, 'creator_id': None, 'creator': None, 'raw_name': 'Mengshi Wu', 'given_name': 'Mengshi', 'surname': 'Wu', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 4, 'creator_id': None, 'creator': None, 'raw_name': 'Tabata Rosas-Diaz', 'given_name': 'Tabata', 'surname': 'Rosas-Diaz', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 5, 'creator_id': None, 'creator': None, 'raw_name': 'Liping Wang', 'given_name': 'Liping', 'surname': 'Wang', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 6, 'creator_id': None, 'creator': None, 'raw_name': 'Xue Ding', 'given_name': 'Xue', 'surname': 'Ding', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 7, 'creator_id': None, 'creator': None, 'raw_name': 'Dan Zhang', 'given_name': 'Dan', 'surname': 'Zhang', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 8, 'creator_id': None, 'creator': None, 'raw_name': 'Xing Fu', 'given_name': 'Xing', 'surname': 'Fu', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 9, 'creator_id': None, 'creator': None, 'raw_name': 'Chanhong Kim', 'given_name': 'Chanhong', 'surname': 'Kim', 'role': 'author', 'raw_affiliation': None, 'extra': None}
{'index': 10, 'creator_id': None, 'creator': None, 'raw_name': 'Rosa Lozano-Duran', 'given_name': 'Rosa', 'surname': 'Lozano-Duran', 'role': 'author', 'raw_affiliation': None, 'extra': None}
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release_date 2019-11-12
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title A novel pathway linking plasma membrane and chloroplasts is co-opted by pathogens to suppress salicylic acid-dependent defences
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