Crowdsourcing Machine Intelligence Solutions to Accelerate Biomedical Science: Lessons learned from a machine intelligence ideation contest to improve the prediction of 3D domain swapping release_eg5zvu76o5f5fhonvkdul4bhpu

by Yash Shah, Deepak Sharma, Rakesh Sharma, Sourav Singh, Hrishikesh Thakur, William John, Shamsudheen Marakkar, Prashanth Suravajhala, Vijayaraghava Seshadri Sundararajan, Jayaraman Valadi, Shameer Khader, Ramanathan Sowdhamini

Released as a post by Cold Spring Harbor Laboratory.

2020  

Abstract

Machine intelligence methods, including natural language processing, computer vision, machine vision, artificial intelligence, and deep learning approaches, are rapidly evolving and play an essential role in biomedicine. Machine intelligence methods could help to accelerate image analyses aid in building complex models capable of interpretation beyond cognitive limitations and statistical assumptions in biomedicine. However, irrespective of the democratization via accessible computing and software modules, machine intelligence handiness is scarce in the setting of a traditional biomedical research laboratory. In such a context, collaborations with bioinformatics and computational biologists may help. Further, the biomedical diaspora could also seek help from the expert communities using a crowdsourcing website that hosts machine intelligence competitions. Machine intelligence competitions offer a vast pool of seasoned data scientists and machine intelligence experts to develop solutions through competition portals. An alternate approach to improve the adoption of machine intelligence in biomedicine is to offer machine intelligence competitions as part of scientific meetings. In this paper, we discuss a structured methodology employed to develop the machine intelligence competition as part of an international bioinformatics conference. The competition leads to developing a novel method through crowdsourcing to solve a challenging problem in biomedicine: predicting probabilities of proteins that undergo 3D domain swapping. As a biomedical science conference focused on computational methods, the competition received multiple entries that ultimately helped improve the predictive modeling of 3D domain swapping using sequence information.
In application/xml+jats format

Archived Files and Locations

application/pdf  1.8 MB
file_3cfr6q365zeongvposnb2lakrm
www.biorxiv.org (repository)
web.archive.org (webarchive)
Read Archived PDF
Preserved and Accessible
Type  post
Stage   unknown
Date   2020-07-12
Work Entity
access all versions, variants, and formats of this works (eg, pre-prints)
Catalog Record
Revision: 888e1692-7853-4c8e-b566-df26caf5f015
API URL: JSON