via crossref
|
Engineered human cardiac microtissues: The state-of-the-(he)art
Kayla Soon, Omar Mourad, Sara S Nunes Vasconcelos 2021
Stem Cells
doi:10.1002/stem.3376
pmid:33786918
|
|
via fatcat-pubmed
|
Development of Novel Glucocorticoids for Use in Antibody–Drug Conjugates for the Treatment of Inflammatory Diseases
Amy Han, Olav Olsen, Christopher D'Souza, Jing Shan, Feng Zhao, Jean Yanolatos, Zaruhi Hovhannisyan, Sokol Haxhinasto (+ more) 2021
Journal of Medicinal Chemistry
doi:10.1021/acs.jmedchem.1c00541
pmid:34378927
|
|
via crossref
|
Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening environment
Maria Giustina Rotordam, Alison Obergrussberger, Nina Brinkwirth, Kiyoshi Takasuna, Nadine Becker, András Horváth, Tom A. Goetze, Markus Rapedius (+ more) 2021
Journal of pharmacological and toxicological methods
doi:10.1016/j.vascn.2021.107125
pmid:34500078
|
|
via crossref
|
Repurposing Infectious Disease Hits as Anti-Cryptosporidium Leads
Matthew A. Hulverson, Ryan Choi, Molly C. McCloskey, Grant R. Whitman, Kayode K. Ojo, Samantha A. Michaels, Mastanbabu Somepalli, Melissa S. Love (+ more) 2021
ACS Infectious Diseases
doi:10.1021/acsinfecdis.1c00076
pmid:33740373
|
|
via crossref
|
Proteome and Membrane Channels
[chapter]
Alberto Pasquarelli 2021
A Practical Guide to Pharmacological Biotechnology
doi:10.1007/978-3-030-76469-2_10
|
|
via fatcat-pubmed
|
Flavonoids and hERG channels: friends or foes?
Simona Saponara, Fabio Fusi, Daniele Iovinelli, Amer Ahmed, Alfonso Trezza, Ottavia Spiga, Giampietro Sgaragli, Massimo Valoti 2021
European Journal of Pharmacology
doi:10.1016/j.ejphar.2021.174030
pmid:33727059
|
|
via grobid
|
Pharmacophore-Guided Identification of Natural Products as Potential Inhibitors of Mycobacterium ulcerans Cystathionine γ-Synthase MetB
Samuel K. Kwofie, Nigel N. O. Dolling, Emmanuel Donkoh, Godwin M. Laryea, Lydia Mosi, Whelton A. Miller, Michael B. Adinortey, Michael D. Wilson 2021
Computation
doi:10.3390/computation9030032
|
web.archive.org [PDF]
|
via crossref
|
Genome Sequencing
[chapter]
Alberto Pasquarelli 2021
A Practical Guide to Pharmacological Biotechnology
doi:10.1007/978-3-030-76469-2_9
|
|
via fatcat-pubmed
|
Cardiac hERG K+ Channel as Safety and Pharmacological Target
[chapter]
Shi Su, Jinglei Sun, Yi Wang, Yanfang Xu 2021
Handbook of Experimental Pharmacology
doi:10.1007/164_2021_455
pmid:33829343
|
|
via crossref
|
Intracellular Potassium Ion Fluorescent Nanoprobes for Functional Analysis of hERG Channel via Bioimaging
Tingting Pan, Min Shen, Jiayan Shi, Juewei Ning, Fengyu Su, Jianxiang Liao, Yanqing Tian 2021
Sensors and actuators. B, Chemical
doi:10.1016/j.snb.2021.130450
|
|
via fatcat-pubmed
|
Machine Learning Strategies When Transitioning between Biological Assays
Staffan Arvidsson McShane, Ernst Ahlberg, Tobias Noeske, Ola Spjuth 2021
Journal of Chemical Information and Modeling
doi:10.1021/acs.jcim.1c00293
pmid:34152755
|
|
via crossref
|
Pyrrolopyrimidine Bumped Kinase Inhibitors for the Treatment of Cryptosporidiosis
Matthew A Hulverson, Ryan Choi, Rama S R Vidadala, Grant R Whitman, Venkata Narayana Vidadala, Kayode K Ojo, Lynn K Barrett, James J Lynch (+ more) 2021
ACS Infectious Diseases
doi:10.1021/acsinfecdis.0c00803
pmcid:PMC8559537
pmid:33565854
|
|
via grobid
|
Transgenic Rabbit Models in Proarrhythmia Research.
István Baczkó, Tibor Hornyik, Michael Brunner, Gideon Koren, Katja E. Odening 2020
doi:10.7892/boris.147827
|
web.archive.org [PDF]
|
via crossref
|
Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment
Nina Brinkwirth, Kiyoshi Takasuna, Masafumi Doi, Nadine Becker, Alison Obergrussberger, Søren Friis, Hatsue Furukawa, Yuka Hasegawa (+ more) 2020
Journal of pharmacological and toxicological methods
doi:10.1016/j.vascn.2020.106884
pmid:32565325
|
|
via fatcat-pubmed
|
Transgenic Rabbit Models in Proarrhythmia Research
István Baczkó, Tibor Hornyik, Michael Brunner, Gideon Koren, Katja E. Odening 2020
Frontiers in Pharmacology
doi:10.3389/fphar.2020.00853
pmcid:PMC7291951
pmid:32581808
|
web.archive.org [PDF]
|
via crossref
|
preADMET analysis and clinical aspects of dogs treated with the organotellium compound RF07: a possible control for canine visceral leishmaniasis?
Adriana Maria Viana Nunes, Franscisco da Chagas Pereira de Andrade, Livia Alves Filgueiras, Octávio Augusto de Carvalho Maia, Rodrigo L.O.R. Cunha, Sindy V.A. Rodezno, Antônio Luiz Martins Maia Filho, Fernando Aécio de Amorim Carvalho (+ more) 2020
Environmental Toxicology and Pharmacology
doi:10.1016/j.etap.2020.103470
pmid:32814174
|
|
via fatcat-pubmed
|
Virtual screening and molecular simulation study of natural products database for lead identification of novel coronavirus main protease inhibitors
Nancy Tripathi, Bharat Goel, Nivedita Bhardwaj, Bharat Sahu, Hemant Kumar, Shreyans K. Jain 2020
Journal of Biomolecular Structure and Dynamics
doi:10.1080/07391102.2020.1848630
pmid:33213294
|
|
via crossref
|
Transgenic LQT2, LQT5 and LQT2-5 rabbit models with decreased repolarisation reserve for prediction of drug-induced ventricular arrhythmias
Tibor Hornyik, Alessandro Castiglione, Gerlind Franke, Stefanie Perez-Feliz, Péter Major, László Hiripi, Gideon Koren, Zsuzsanna Bősze (+ more) 2020
British Journal of Pharmacology
doi:10.1111/bph.15098
pmid:32436214
|
|
via crossref
|
In silico approach in the assessment of chromatographic parameters as descriptors of diphenylacetamides' biological/pharmacological profile
Suzana Apostolov, Dušan Mijin, Slobodan Petrović, Gyöngyi Vastag 2020
Journal of Liquid Chromatography & Related Technologies
doi:10.1080/10826076.2020.1835672
|
|
via grobid
|
Antibacterial activity of novel dual bacterial DNA type II topoisomerase inhibitors
Noemi D'Atanasio, Alessandra Capezzone de Joannon, Laura Di Sante, Giorgina Mangano, Rosella Ombrato, Marco Vitiello, Cristina Bartella, Gabriele Magarò (+ more) 2020
PLoS ONE
doi:10.1371/journal.pone.0228509
pmcid:PMC7029851
pmid:32074119
|
web.archive.org [PDF]
|
via fatcat-pubmed
|
Capsule Networks Showed Excellent Performance in the Classification of hERG Blockers/Nonblockers
Yiwei Wang, Lei Huang, Siwen Jiang, Yifei Wang, Jun Zou, Hongguang Fu, Shengyong Yang 2020
Frontiers in Pharmacology
doi:10.3389/fphar.2019.01631
pmcid:PMC6997788
pmid:32063849
|
web.archive.org [PDF]
|
via crossref
|
Micro-patterned SU-8 cantilever integrated with metal electrode for enhanced electromechanical stimulation of cardiac cells
Nomin-Erdene Oyunbaatar, Arunkumar Shanmugasundaram, Yun-Jin Jeong, Bong-Kee Lee, Eung-Sam Kim, Dong-Weon Lee 2020
Colloids and Surfaces B: Biointerfaces
doi:10.1016/j.colsurfb.2019.110682
pmid:31846891
|
|
via crossref
|
Emerging neurotechnology for antinoceptive mechanisms and therapeutics discovery
Bryan J. Black, Rahul Atmaramani, Sarah Plagens, Zachary T. Campbell, Gregory Dussor, Theodore J. Price, Joseph J. Pancrazio 2019
Biosensors & bioelectronics
doi:10.1016/j.bios.2018.11.015
pmcid:PMC6791128
pmid:30544081
|
|
via fatcat-pubmed
|
Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology
Heather B. Hayes, Anthony M. Nicolini, Colin A. Arrowood, Stacie A. Chvatal, David W. Wolfson, Hee Cheol Cho, Denise D. Sullivan, Jérome Chal (+ more) 2019
Scientific Reports
doi:10.1038/s41598-019-48174-5
pmcid:PMC6695445
pmid:31417144
|
web.archive.org [PDF]
|
via crossref
|
hERG Liability Classification Models Using Machine Learning Techniques
Konda Leela Sarath Kumar, S. Keerthi Praba, Rajendra Kristam 2019
Computational Toxicology
doi:10.1016/j.comtox.2019.100089
|
|
via crossref
|
Synthesis and anti-tumor activity of imidazopyrazines as TAK1 inhibitors
Seok Jong Kang, Jung Wuk Lee, Shin Hyuck Chung, Sun Young Jang, Jaeyul Choi, Kwee Hyun Suh, Young Hoon Kim, Young Jin Ham (+ more) 2019
European Journal of Medicinal Chemistry
doi:10.1016/j.ejmech.2018.12.025
|
|
via crossref
|
Discovery of Novel Alpha-Amylase Inhibitors for Type II Diabetes Mellitus Through the Fragment-Based Drug Design
[chapter]
Yulianti, Agustinus Corona Boraelis Kantale, Usman Sumo Friend Tambunan 2019
Lecture Notes in Computer Science
doi:10.1007/978-3-030-17938-0_3
|
|
via crossref
|
First-in-class DAPK1/CSF1R dual inhibitors: Discovery of 3,5-dimethoxy-N-(4-(4-methoxyphenoxy)-2-((6-morpholinopyridin-3-yl)amino)pyrimidin-5-yl)benzamide as a potential anti-tauopathies agent
Ahmed Karam Farag, Ahmed H.E. Hassan, Hyeanjeong Jeong, Youngji Kwon, Jin Gyu Choi, Myung Sook Oh, Ki Duk Park, Yun Kyung Kim (+ more) 2019
European Journal of Medicinal Chemistry
doi:10.1016/j.ejmech.2018.10.057
|
|
via crossref
|
Design, synthesis and biological evaluation of novel thiazolidinedione derivatives as irreversible allosteric IKK-β modulators
Ahmed Elkamhawy, Nam youn Kim, Ahmed H.E. Hassan, Jung-eun Park, Jeong-Eun Yang, Kwang-Seok Oh, Byung Ho Lee, Mi Young Lee (+ more) 2018
European Journal of Medicinal Chemistry
doi:10.1016/j.ejmech.2018.08.020
pmid:30130718
|
|
via fatcat-pubmed
|
Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis
Matthew A Hulverson, Igor Bruzual, Erin V McConnell, Wenlin Huang, Rama S R Vidadala, Ryan Choi, Samuel L M Arnold, Grant R Whitman (+ more) 2018
Journal of Infectious Diseases
doi:10.1093/infdis/jiy664
pmid:30423128
|
|