Inhibitory Activity of Plant Extracts on Aflatoxin B 1 Biosynthesis by Aspergillus flavus release_bypmcsn5k5em5lknu7nqkz4zbe

Abstract

The inhibitory activities of aqueous and solvent extracts of twelve selected medicinal plants were evaluated against biosynthesis of aflatoxin B 1 (AFB 1) by Aspergillus flavus. The A. flavus was isolated from maize, and aflatoxin B 1 biosynthesis was confirmed by comparison with standard AFB 1 using TLC method. In vivo antiaflatoxigenic efficacies of activity guided solvent extracts were determined in maize model system. All the extracts showed varying degree of antifungal and AFB 1 inhibitory activities, but chloroformic extract of Albizia amara, Cassia spectabilis and Solanum indicum, and methanolic extract of Acacia catechu, Albizia saman and Anogeissus latifolia showed the highest activity. Further investigations on identification of active principles from these plants are needed to develop plant based formulations for management of A. flavus growth and AFB 1 contamination in food grains.
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