{"DOI":"10.1515/znc-2000-9-1008","abstract":"Abstract\n\t\t\t\t Two cytotoxic terpenes, \u03b1-santonin (1) and sclareol (3) were biotransformed by a plant pathogenic fungus Botrytis cinerea to produce oxidized metabolites in high yields. \u03b1-Santonin (1 ) on fermentation with the fungus for ten days afforded a hydroxylated metabolite identified as 11\u03b2-hydroxy-\u03b1-santonin (2) in a high yield (83%), while sclareol (3) was metabolized to epoxysclareol (4) (64%) and a new compound 8-deoxy-14,15-dihydro-15-chloro-14-hydroxy- 8,9-dehydrosclareol (5) (7%), representing a rare example of microbial halogenation.","author":[{"family":"Farooq"},{"family":"Tahara"}],"id":"unknown","issue":"9-10","issued":{"date-parts":[[2000,10,1]]},"page-first":"713","publisher":"Walter de Gruyter GmbH","title":"Biotransformation of Two Cytotoxic Terpenes, \u03b1-Santonin and Sclareol by Botrytis cinerea","type":"article-journal","volume":"55"}