Risk Factors for Sudden Infant Death in North Carolina release_7iu4f4e4pvblzljxbjeu7hluqe

by Merick M. Yamada, Michael B. Rosamilia, Karen E. Chiswell, Alfred D'Ottavio, Tracy Spears, Claire Osgood, Marie Lynn Miranda, Nina Forestieri, Jennifer S. Li, Andrew P. Landstrom

Published in Frontiers in Pediatrics by Frontiers Media SA.

2021   Volume 9, p770803

Abstract

<jats:bold>Background:</jats:bold> Sudden infant death syndrome (SIDS) is the sudden, unexplained death of infants &amp;lt;1 year old. SIDS remains a leading cause of death in US infants. We aim to identify associations between SIDS and race/ethnicity, birth weight/gestational age, and socioeconomic/environmental factors in North Carolina (NC) to help identify infants at risk for SIDS.<jats:bold>Methods and Results:</jats:bold> In this IRB-approved study, infant mortality 2007–2016 and death certificate-linked natality 2007–2014 were obtained from the NC Department of Health and Human Services. General, NC natality statistics 2007–2016 were obtained from CDC Wonder. Association between SIDS/total infant death and covariates (below) were calculated. Total infant mortality decreased 2007–2016 by an average of 14 deaths/100,000 live births per year, while SIDS incidence remained constant. Risk ratios of SIDS/total infant deaths, standardized to Non-Hispanic White, were 1.76/2.41 for Non-Hispanic Black and 0.49/0.97 for Hispanic infants. Increased SIDS risk was significantly and independently associated with male infant sex, Non-Hispanic Black maternal race/ethnicity, young maternal age, low prenatal care, gestational age &amp;lt;39 weeks, birthweight &amp;lt;2500 g, low maternal education, and maternal tobacco use (<jats:italic>p</jats:italic> &amp;lt; <jats:italic>0.01</jats:italic>). Maternal previous children now deceased also trended toward association with increased SIDS risk.<jats:bold>Conclusions:</jats:bold> A thorough SIDS risk assessment should include maternal, socioeconomic, and environmental risk factors as these are associated with SIDS in our population.
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