Declines in grip strength may indicate early changes in cognition in healthy middle-aged adults release_7flvztrj55czvc55kjgvxjsc4y

by Diane E. Adamo, Tara Anderson, Mahtab Koochaki, Nora Fritz

Published in PLoS ONE by Public Library of Science (PLoS).

2020   Volume 15, Issue 4, e0232021

Abstract

Declining grip strength is an indicator of cognitive loss in older individuals but it has not been explored people younger than 65 years old. The purpose of this study was to investigate the relationship between grip strength and specific cognitive tests known to decline with mild cognitive impairment in young and middle-aged adults. Declines in cognitive performance in middle-aged adults may provide evidence that these changes occur earlier than previously reported. A cross sectional design was used to compare differences between young and middle-aged healthy adults and to investigate associations between cognitive and grip strength measures within groups. Healthy young (20-30 years old) and middle-aged (45-65 years old) adults completed five cognitive tests including the Stroop, California Verbal Learning Test, Symbol Digit Modalities Test, Trail Making Tests and the Controlled Oral Word Association Test. All participants completed right and left maximum grip strength measures. Middle-aged adults performed significantly worse on right and left grip strength and the Stroop test (p<0.05) when compared to the younger group. There were no significant relationships among grip strength and cognitive performance at the whole-group level or within the younger-age group; however, weaker grip strength was significantly associated with poorer Controlled Oral Word Association Test total cluster (r = 0.458; p < .05) and Stroop interference (r = 0.471; p < .05) scores in the middle-aged group. Findings from this study suggest that cognitive changes may occur earlier than previously thought (prior to age 65). Weaker grip strength was significantly associated with poorer function in two of the cognitive measures in the middle-age group, suggesting that some domains of cognition, specifically semantic categorization and executive function, may be particularly sensitive to age-related changes.
In text/plain format

Archived Files and Locations

application/pdf  658.9 kB
file_obbgc7pwwnhspplivjyz6okzfi
journals.plos.org (publisher)
web.archive.org (webarchive)
Read Archived PDF
Preserved and Accessible
Type  article-journal
Stage   published
Date   2020-04-23
Language   en ?
Container Metadata
Open Access Publication
In DOAJ
Not in Keepers Registry
ISSN-L:  1932-6203
Work Entity
access all versions, variants, and formats of this works (eg, pre-prints)
Catalog Record
Revision: e8452cc2-087c-4d13-8c53-a3987e04d8e4
API URL: JSON