Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device release_5gedgg66kbftpnpmaoudvr6h4a

by Byeong-Heon Kil, Ji-Seong Park, Munho Ryu, Chan-Young Park, Yu-Seop Kim, Jong-Dae Kim

Published in Sensors by MDPI AG.

2021   Volume 21, Issue 21, p6980

Abstract

This paper proposes a cloud-based software architecture for fully automated point-of-care molecular diagnostic devices. The target system operates a cartridge consisting of an extraction body for DNA extraction and a PCR chip for amplification and fluorescence detection. To facilitate control and monitoring via the cloud, a socket server was employed for fundamental molecular diagnostic functions such as DNA extraction, amplification, and fluorescence detection. The user interface for experimental control and monitoring was constructed with the RESTful application programming interface, allowing access from the terminal device, edge, and cloud. Furthermore, it can also be accessed through any web-based user interface on smart computing devices such as smart phones or tablets. An emulator with the proposed software architecture was fabricated to validate successful operation.
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Type  article-journal
Stage   published
Date   2021-10-21
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DOI  10.3390/s21216980
PubMed  34770286
PMC  PMC8587904
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