Anorexia nervosa release_37rdhvn2pvcqffir7dnrgekffa

by Kathleen Kara Fitzpatrick, James Lock

Published in Clinical evidence .

Volume 2011 (2011)

Abstract

Anorexia nervosa is characterised by a low body mass index (BMI), fear of gaining weight, denial of current low weight and its impact on health, and amenorrhoea. Estimated prevalence is highest in teenage girls, and up to 0.7% of this age group may be affected. While most people with anorexia nervosa recover completely or partially, about 5% die of the condition, and 20% develop a chronic eating disorder. Young women with anorexia nervosa are at increased risk of bone fractures later in life. We conducted a systematic review, and aimed to answer the following clinical questions: What are the effects of treatments in anorexia nervosa? What are the effects of interventions to prevent or treat complications of anorexia nervosa? We searched: Medline, Embase, The Cochrane Library, and other important databases up to April 2010 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). We found 40 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. In this systematic review we present information relating to the effectiveness and safety of the following interventions: atypical antipsychotic drugs, benzodiazepines, cyproheptadine, inpatient/outpatient treatment setting, oestrogen treatment (HRT or oral contraceptives), older-generation antipsychotic drugs, psychotherapy, refeeding, selective serotonin reuptake inhibitors (SSRIs), and tricyclic antidepressants.
In text/plain format

Archived Files and Locations

application/pdf  336.3 kB
file_qnsvtmjoorhutdfa3ithh3hkiy
web.archive.org (webarchive)
europepmc.org (repository)
Read Archived PDF
Archived
Type  article-journal
Stage   published
Date   2011-04-11
Language   en ?
PubMed  21481284
PMC  PMC3275304
Container Metadata
Not in DOAJ
In Keepers Registery
ISSN-L:  1462-3846
Work Entity
access all versions, variants, and formats of this works (eg, pre-prints)
Catalog Record
Revision: c4ea1357-c425-4bd3-9640-34129944527e
API URL: JSON