Early transient intraocular pressure spike after cataract surgery in highly myopic cataract eyes and associated risk factors release_cihh5phxwzcwjdudnq353avnlm [as of editgroup_5oylmnzbxzd37pdl6xpwcttje4]

by Xiangjia Zhu, Jiao Qi, Wenwen He, Shaohua Zhang, Keke Zhang, Qiang Lu, Yi Lu

Published in British Journal of Ophthalmology by BMJ.

2019   bjophthalmol-2019-315117

Abstract

<jats:sec><jats:title>Purpose</jats:title>To investigate the incidence of the early transient intraocular pressure (IOP) spike after cataract surgery in eyes with highly myopic cataract (HMC) and associated risk factors.</jats:sec><jats:sec><jats:title>Methods</jats:title>Consecutive patients treated with phacoemulsification were recruited. IOP was measured before and 1 day, 3 days, 1 week and 3 months after surgery. Axial length (AL) and anterior chamber depth (ACD) were recorded, and optic disc tilt, rotation and beta-zone peripapillary atrophy (β-PPA) were measured from fundus photographs taken 1 week after surgery. Backward stepwise multiple linear regression was used to investigate the risk factors for early transient IOP spike in the HMC group.</jats:sec><jats:sec><jats:title>Results</jats:title>Finally, 94 eyes of 94 HMC patients and 67 eyes of 67 age-related cataract (ARC) controls were included in analysis. The incidence of early IOP spike was 10% in the ARC group and 28% in the HMC group (OR=3.277, p&lt;0.05) at 1 day after surgery. In the HMC group with IOP spikes, more males were seen and affected eyes showed longer AL, shallower ACD, greater optic disc tilt, and larger β-PPA than those without (all p&lt;0.05). Multivariate analysis showed that sex, AL, ACD, and area of β-PPA were significantly associated with an early transient IOP spike in HMC eyes (all p&lt;0.05).</jats:sec><jats:sec><jats:title>Conclusions</jats:title>Highly myopic eyes are more susceptible to early transient IOP spike after cataract surgery, and male sex, longer AL, shallower ACD, and greater β-PPA are associated risk factors.</jats:sec><jats:sec><jats:title>Clinical trial registration number</jats:title><jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="clintrialgov" xlink:href="NCT02182921">NCT02182921</jats:ext-link>.</jats:sec>
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Stage   published
Date   2019-11-08
Language   en ?
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